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Tumor Suppressor WWOX Contributes to the Elimination of Tumorigenic Cells in Drosophila melanogaster.

WWOX is a >1 Mb gene spanning FRA16D Common Chromosomal Fragile Site, a region of DNA instability in cancer. Consequently, altered WWOX levels have been observed in a wide variety of cancers. In vitro studies have identified a large number and variety of potential roles for WWOX. Although its normal...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Louise V O'Keefe, Cheng Shoou Lee, Amanda Choo, Robert I Richards
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2015-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:http://europepmc.org/articles/PMC4547717?pdf=render
Tagiau: Ychwanegu Tag
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