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Differential repression of alternative transcripts: a screen for miRNA targets.

Alternative polyadenylation sites produce transcript isoforms with 3' untranslated regions (UTRs) of different lengths. If a microRNA (miRNA) target is present in the UTR, then only those target-containing isoforms should be sensitive to control by a cognate miRNA. We carried out a systematic examin...

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Bibliografiske detaljer
Principais autores: Matthieu Legendre, William Ritchie, Fabrice Lopez, Daniel Gautheret
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2006-05-01
Serier:PLoS Computational Biology
Online adgang:https://doi.org/10.1371/journal.pcbi.0020043
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