Targeting cAMP in D1-MSNs in the nucleus accumbens, a new rapid antidepressant strategy

Studies have suggested that the nucleus accumbens (NAc) is implicated in the pathophysiology of major depression; however, the regulatory strategy that targets the NAc to achieve an exclusive and outstanding anti-depression benefit has not been elucidated. Here, we identified a specific reduction of...

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Autors principals:	Yue Zhang, Jingwen Gao, Na Li, Peng Xu, Shimeng Qu, Jinqian Cheng, Mingrui Wang, Xueru Li, Yaheng Song, Fan Xiao, Xinyu Yang, Jihong Liu, Hao Hong, Ronghao Mu, Xiaotian Li, Youmei Wang, Hui Xu, Yuan Xie, Tianming Gao, Guangji Wang, Jiye Aa
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2024-02-01
Col·lecció:	Acta Pharmaceutica Sinica B
Matèries:	cAMP Nucleus accumbens Depression D1-MSN D2-MSN Rapid antidepressant
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2211383523004732
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