RapidAIM: a culture- and metaproteomics-based Rapid Assay of Individual Microbiome responses to drugs

Abstract Background Human-targeted drugs may exert off-target effects or can be repurposed to modulate the gut microbiota. However, our understanding of such effects is limited due to a lack of rapid and scalable assay to comprehensively assess microbiome responses to drugs. Drugs and other compound...

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Detalles Bibliográficos

Autores principales:	Leyuan Li, Zhibin Ning, Xu Zhang, Janice Mayne, Kai Cheng, Alain Stintzi, Daniel Figeys
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2020-03-01
Colección:	Microbiome
Materias:	Gut microbiome Drug response In vitro culturing Metaproteomics Absolute abundance Functional profile
Acceso en línea:	http://link.springer.com/article/10.1186/s40168-020-00806-z
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