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Residues 27T and 297A in VP2 contribute to the enhanced replication and pathogenicity of raccoon dog parvovirus

ABSTRACT Raccoon dog parvovirus (RDPV) is a highly contagious pathogen causing severe hemorrhagic enteritis that is fatal in young raccoon dogs. Since 2016, epidemiological investigations have documented recurrent outbreaks of RDPV, exhibiting heightened virulence; however, the molecular mechanisms...

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Tallennettuna:
Päätekijät: Liwen Xu, Wenyu Cao, Yawen Liu, Bo Hu, Chengqi Zhang, Shuangshuang Li, Jiajia Liu, Jianhai Fu, Zichuang Zhang, Yajie Sun, Guanyu Zhao, Xiaoyu Deng, Rongguang Lu, Xue Bai
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2025-10-01
Sarja:Journal of Virology
Aiheet:
parvovirus
capsid
mutation
pathogenicity
replication
receptor
Linkit:https://journals.asm.org/doi/10.1128/jvi.01012-25
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