A twin study of mitochondrial DNA polymorphisms shows that heteroplasmy at multiple sites is associated with mtDNA variant 16093 but not with zygosity.

The mitochondrial theory of ageing proposes that damage to mitochondria and diminished mitochondrial DNA (mtDNA) repair are major contributors to cellular dysfunction and age-related diseases. We investigate the prevalence of heteroplasmy in the mtDNA control region in buccal swab and blood derived...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Toby Andrew, Cassandra D Calloway, Sarah Stuart, Sang Hoon Lee, Raj Gill, Gail Clement, Philip Chowienczyk, Tim D Spector, Ana M Valdes
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2011-01-01
coleção:	PLoS ONE
Acesso em linha:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0022332&type=printable
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!