Increased mitochondrial free Ca2+ during ischemia is suppressed, but not eliminated by, germline deletion of the mitochondrial Ca2+ uniporter

Summary: Mitochondrial Ca2+ overload is proposed to regulate cell death via opening of the mitochondrial permeability transition pore. It is hypothesized that inhibition of the mitochondrial Ca2+ uniporter (MCU) will prevent Ca2+ accumulation during ischemia/reperfusion and thereby reduce cell death...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Courtney E. Petersen, Junhui Sun, Kavisha Silva, Anna Kosmach, Robert S. Balaban, Elizabeth Murphy
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2023-07-01
Цуврал:	Cell Reports
Нөхцлүүд:	CP: Developmental biology
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S2211124723007465
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!