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Zinc metabolism and its role in immunity status in subjects with trisomy 21: chromosomal dosage effect

IntroductionTrisomy 21 (T21), which causes Down syndrome (DS), is the most common chromosomal aneuploidy in humankind and includes different clinical comorbidities, among which the alteration of the immune system has a heavy impact on patient’s lives. A molecule with an important role in immune resp...

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Principais autores: Giuseppe Ramacieri, Chiara Locatelli, Michela Semprini, Maria Chiara Pelleri, Maria Caracausi, Allison Piovesan, Michela Cicilloni, Marco Vigna, Lorenza Vitale, Giacomo Sperti, Luigi Tommaso Corvaglia, Gian Luca Pirazzoli, Pierluigi Strippoli, Francesca Catapano, Beatrice Vione, Francesca Antonaros
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-04-01
coleção:Frontiers in Immunology
Assuntos:
down syndrome
zinc
immunity disorder
transcriptome
integration
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1362501/full
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