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The SRC/NF‐κB‐AKT/NOS3 axis as a key mediator of Kaempferol's protective effects against oxidative stress‐induced osteoclastogenesis

Abstract Background Osteoclasts are integral to the advancement of osteoporosis (OP), and their generation under conditions of oxidative stress (OS) involves various pathways. However, the specific mechanism through which the natural antioxidant kaempferol (KAE) mitigates the influence of OS on oste...

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Principais autores: Jiaming Shen, Chunjie Hu, Yuelong Wang, Yiying Tan, Xiaochen Gao, Nanxi Zhang, Jingwei Lv, Jiaming Sun
Formato: Artigo
Idioma:Inglês
Publicado: Wiley 2024-10-01
Series:Immunity, Inflammation and Disease
Assuntos:
Kaempferol
osteoclasts
osteoporosis
oxidative stress
SRC/NF‐κB‐AKT/NOS3 axis
Acceso en liña:https://doi.org/10.1002/iid3.70045
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