CYP51C Y319H and H349R substitutions cannot confer azole resistance in Aspergillus flavus NRRL 3357-5
ABSTRACT Azole antifungals inhibit the cytochrome P450-dependent lanosterol 14-α-demethylase (CYP51), an essential enzyme in the ergosterol biosynthetic pathway. While azole resistance mechanisms are well established in Aspergillus fumigatus, the molecular basis of resistance in Aspergillus flavus r...
Na minha lista:
| Principais autores: | , , , , |
|---|---|
| 格式: | Artigo |
| 语言: | Inglês |
| 出版: |
American Society for Microbiology
2026-07-01
|
| 丛编: | Microbiology Spectrum |
| 主题: | |
| 在线阅读: | https://journals.asm.org/doi/10.1128/spectrum.00425-26 |
| 标签: |
没有标签, 成为第一个标记此记录!
|