aRNAque: an evolutionary algorithm for inverse pseudoknotted RNA folding inspired by Lévy flights

Abstract Background We study in this work the inverse folding problem for RNA, which is the discovery of sequences that fold into given target secondary structures. Results We implement a Lévy mutation scheme in an updated version of aRNAque an evolutionary inverse folding algorithm and apply it to...

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Autori principali:	Nono S. C. Merleau, Matteo Smerlak
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2022-08-01
Serie:	BMC Bioinformatics
Soggetti:	RNA inverse folding Pseudoknotted RNAs Evolutionary algorithm (EA) Lévy flight
Accesso online:	https://doi.org/10.1186/s12859-022-04866-w
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