A Conserved Hydrophobic Moiety and Helix–Helix Interactions Drive the Self-Assembly of the Incretin Analog Exendin-4

Exendin-4 is a pharmaceutical peptide used in the control of insulin secretion. Structural information on exendin-4 and related peptides especially on the level of quaternary structure is scarce. We present the first published association equilibria of exendin-4 directly measured by static and dynam...

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Bibliografski detalji

Glavni autori:	Martin Wolff, Klaus Gast, Andreas Evers, Michael Kurz, Stefania Pfeiffer-Marek, Anja Schüler, Robert Seckler, Anja Thalhammer
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2021-09-01
Serija:	Biomolecules
Teme:	biophysics diabetes peptides oligomerization conformational change molecular modeling
Online pristup:	https://www.mdpi.com/2218-273X/11/9/1305
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