Plasmodium falciparum Calcium-Dependent Protein Kinase 4 is Critical for Male Gametogenesis and Transmission to the Mosquito Vector

ABSTRACT Gametocytes of the malaria parasite Plasmodium are taken up by the mosquito vector with an infectious blood meal, representing a critical stage for parasite transmission. Calcium-independent protein kinases (CDPKs) play key roles in calcium-mediated signaling across the complex life cycle o...

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Autori principali:	Sudhir Kumar, Meseret T. Haile, Michael R. Hoopmann, Linh T. Tran, Samantha A. Michaels, Seamus R. Morrone, Kayode K. Ojo, Laura M. Reynolds, Ulrike Kusebauch, Ashley M. Vaughan, Robert L. Moritz, Stefan H. I. Kappe, Kristian E. Swearingen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2021-12-01
Serie:	mBio
Soggetti:	PfCDPK4 exflagellation gametocyte mosquito transmission phosphoproteome
Accesso online:	https://journals.asm.org/doi/10.1128/mBio.02575-21
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