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The prognostic role of Claudin 18.2 in advanced gastric or gastroesophageal junction adenocarcinoma: a systematic literature review

Claudin 18 isoform 2 (CLDN18.2) is a tight junction protein expressed in normal gastric tissue and retained in gastric or gastroesophageal junction (G/GEJ) adenocarcinoma. The phase III trials SPOTLIGHT and GLOW demonstrated improved survival following the addition of the CLDN18.2-targeted antibody...

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Bibliografische gegevens
Hoofdauteurs: M. Fassan, I. Chau, H. Dasghaib, J. Hill, R. Pophale, K. Shitara
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2025-09-01
Reeks:ESMO Gastrointestinal Oncology
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Online toegang:http://www.sciencedirect.com/science/article/pii/S2949819825000792
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