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FK506-binding protein, FKBP12, promotes serine utilization and negatively regulates threonine deaminase in fission yeast

Summary: FK506-binding protein with a molecular weight of 12 kDa (FKBP12) is a receptor of the immunosuppressive drugs, FK506 and rapamycin. The physiological functions of FKBP12 remain ambiguous because of its nonessentiality and multifunctionality. Here, we show that FKBP12 promotes the utilizatio...

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Hauptverfasser: Mayuki Sasaki, Shinichi Nishimura, Yoko Yashiroda, Akihisa Matsuyama, Hideaki Kakeya, Minoru Yoshida
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2022-12-01
Schriftenreihe:iScience
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2589004222019319
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