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Role of the ISKpn element in mediating mgrB gene mutations in ST11 hypervirulent colistin-resistant Klebsiella pneumoniae

BackgroundColistin has emerged as a last-resort therapeutic against antibiotic-resistant bacterial infections, particularly those attributed to carbapenem-resistant Enterobacteriaceae (CRE) like CRKP. Yet, alarmingly, approximately 45% of multidrug-resistant Klebsiella pneumoniae strains now manifes...

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Principais autores: Lanlan Zhu, Ping Li, Guangyi Zhang, Zhiyong He, Xingyu Tao, Yicheng Ji, Wenjing Yang, Xiaofang Zhu, Wanying Luo, Wenjian Liao, Chuanhui Chen, Yang Liu, Wei Zhang
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2023-09-01
סדרה:Frontiers in Microbiology
נושאים:
colistin-resistant Klebsiella pneumoniae
ISKpn
mgrB
ST11
hypervirulent
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1277320/full
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