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Improvement of Duchenne muscular dystrophy phenotype following obestatin treatment

Abstract Background This study was performed to test the therapeutic potential of obestatin, an autocrine anabolic factor regulating skeletal muscle repair, to ameliorate the Duchenne muscular dystrophy (DMD) phenotype. Methods and results Using a multidisciplinary approach, we characterized the age...

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Principais autores: Jessica González‐Sánchez, Agustín Sánchez‐Temprano, Tania Cid‐Díaz, Regina Pabst‐Fernández, Carlos S. Mosteiro, Rosalía Gallego, Ruben Nogueiras, Xesús Casabiell, Gillian S. Butler‐Browne, Vincent Mouly, José Luis Relova, Yolanda Pazos, Jesús P. Camiña
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2018-12-01
coleção:Journal of Cachexia, Sarcopenia and Muscle
Assuntos:
Duchenne muscular dystrophy
Skeletal muscle cell atrophy
Pharmacological modifier
Obestatin signalling
Skeletal muscle
Acesso em linha:https://doi.org/10.1002/jcsm.12338
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