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Genomic heterozygosity is associated with a lower risk of osteoarthritis

Abstract Background Genomic heterozygosity has been shown to confer a health advantage in humans and play a protective role in complex diseases. Given osteoarthritis (OA) is a highly polygenic disease, we set out to determine if an association exists between OA and genomic heterozygosity. Results En...

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Principais autores: Robert Gill, Ming Liu, Guang Sun, Andrew Furey, Tim Spector, Proton Rahman, Guangju Zhai
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2024-01-01
Series:BMC Genomics
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Acceso en liña:https://doi.org/10.1186/s12864-024-10015-9
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