SIAH1 reverses chemoresistance in epithelial ovarian cancer via ubiquitination of YBX-1

Abstract Chemoresistance is a severe outcome among patients with epithelial ovarian cancer (EOC) that leads to a poor prognosis. YBX-1 has been shown to cause treatment failure and cancer progression in EOC. However, strategies that directly target YBX-1 are not yet conceivable. Here, we identified...

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Autori principali:	Wujiang Gao, Lu Chen, Li Lin, Meiling Yang, Taoqiong Li, Hong Wei, Chunli Sha, Jie Xing, Mengxue Zhang, Shijie Zhao, Qi Chen, Wenlin Xu, Yuefeng Li, Xiaolan Zhu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2022-03-01
Serie:	Oncogenesis
Accesso online:	https://doi.org/10.1038/s41389-022-00387-6
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