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Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide

During screening of genes upregulated by lipopolysaccharide (LPS; endotoxin) treatment of bone marrow-derived mouse macrophages, it was unexpectedly found that cholesterol 25-hydroxylase (Ch25h) was strongly upregulated. Treatment of macrophages with 10 ng/ml of LPS for 2 h resulted in a 35-fold inc...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Ulf Diczfalusy, Katarina E. Olofsson, Ann-Margreth Carlsson, Mei Gong, Douglas T. Golenbock, Olav Rooyackers, Urban Fläring, Harry Björkbacka
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2009-11-01
Schriftenreihe:Journal of Lipid Research
Schlagworte:
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S002222752030691X
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