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Extracellular NAD+ response to post-hepatectomy liver failure: bridging preclinical and clinical findings

Abstract Liver fibrosis progressing to cirrhosis is a major risk factor for liver cancer, impacting surgical treatment and survival. Our study focuses on the role of extracellular nicotinamide adenine dinucleotide (eNAD+) in liver fibrosis, analyzing liver disease patients undergoing surgery. Additi...

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Hoofdauteurs: Can Kamali, Philipp Brunnbauer, Kaan Kamali, Al-Hussein Ahmed Saqr, Alexander Arnold, Gulcin Harman Kamali, Julia Babigian, Eriselda Keshi, Raphael Mohr, Matthäus Felsenstein, Simon Moosburner, Karl-Herbert Hillebrandt, Jasmin Bartels, Igor Maximilian Sauer, Frank Tacke, Moritz Schmelzle, Johann Pratschke, Felix Krenzien
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Portfolio 2024-08-01
Reeks:Communications Biology
Online toegang:https://doi.org/10.1038/s42003-024-06661-0
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