Mechanisms and integrative machine learning approaches to blood–brain barrier biomarker profiling for personalized ischemic stroke management

Abstract Ischemic stroke remains a leading cause of death and disability worldwide, with blood–brain barrier (BBB) disruption playing a central role in vasogenic edema, neuroinflammation, hemorrhagic transformation, and secondary neuronal injury. The BBB is a specialized neurovascular unit composed...

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Autors principals:	John Nzobokela, Lweendo Muchaili, Joy Kaluba Mangimela, Annet Kirabo, Sepiso K. Masenga
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2026-07-01
Col·lecció:	Physiological Reports
Matèries:	biomarkers blood–brain barrier deep learning ischemic stroke LASSO regression machine learning
Accés en línia:	https://doi.org/10.14814/phy2.71003
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