Anti‐β7 integrin treatment impedes the recruitment on non‐classical monocytes to the gut and delays macrophage‐mediated intestinal wound healing

Abstract Background Closing mucosal defects to reach mucosal healing is an important goal of therapy in inflammatory bowel disease (IBD). Among other cells, monocyte‐derived macrophages are centrally involved in such intestinal wound healing. We had previously demonstrated that the anti‐α4β7 integri...

Descripción completa

Detalles Bibliográficos

Autores principales:	Katrin Sommer, Karin Heidbreder, Lucas Kreiss, Mark Dedden, Eva‐Maria Paap, Maximilian Wiendl, Emily Becker, Raja Atreya, Tanja M. Müller, Imke Atreya, Maximilian Waldner, Sebastian Schürmann, Oliver Friedrich, Markus F. Neurath, Sebastian Zundler
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Wiley 2023-04-01
Colección:	Clinical and Translational Medicine
Materias:	etrolizumab gut homing intestinal wound healing monocytes vedolizumab
Acceso en línea:	https://doi.org/10.1002/ctm2.1233
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!