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The Kynurenine Pathway and Kynurenine 3-Monooxygenase Inhibitors

Under normal physiological conditions, the kynurenine pathway (KP) plays a critical role in generating cellular energy and catabolizing tryptophan. Under inflammatory conditions, however, there is an upregulation of the KP enzymes, particularly kynurenine 3-monooxygenase (KMO). KMO has garnered much...

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Príomhchruthaitheoirí: Tamera D. Hughes, Osman F. Güner, Emma Carine Iradukunda, Robert S. Phillips, J. Phillip Bowen
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: MDPI AG 2022-01-01
Sraith:Molecules
Ábhair:
Rochtain ar líne:https://www.mdpi.com/1420-3049/27/1/273
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