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Changes in the orexin system, hypothalamic-pituitary-adrenal axis and circadian rhythm in juvenile-stressed rats

The orexin system has been demonstrated to play various physiological roles, such as in feeding, sleep, and autonomic neural function. Clinically, orexin receptor antagonists are used as hypnotics, and several clinical trials have suggested their efficacy in major depressive disorder. We investigate...

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Hlavní autoři: Kazune Ozaki, Shinya Nishiide, Hiroki Shikanai, Tsugumi Shindo, Riho Mabuchi, Satoshi Shinozuka, Takeshi Izumi
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2026-07-01
Edice:Journal of Pharmacological Sciences
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S1347861326000198
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