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Amoeboid-mesenchymal migration plasticity promotes invasion only in complex heterogeneous microenvironments

Abstract During tissue invasion individual tumor cells exhibit two interconvertible migration modes, namely mesenchymal and amoeboid migration. The cellular microenvironment triggers the switch between both modes, thereby allowing adaptation to dynamic conditions. It is, however, unclear if this amo...

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Detalhes bibliográficos
Principais autores: Katrin Talkenberger, Elisabetta Ada Cavalcanti-Adam, Anja Voss-Böhme, Andreas Deutsch
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2017-08-01
coleção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-017-09300-3
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