Peculiarities of inhibitory receptor expression on effector and regulatory T cells in the context of immune checkpoint inhibitor therapy

Inhibitory receptors PD-1, TIM-3, LAG-3, etc. – “immune checkpoints” – are expressed by activated effector T cells in order to limit the intensity of the immune response. Under the conditions of chronic infectious process and tumor growth, checkpoint receptors are expressed by T lymphocytes in a sta...

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Bibliographic Details

Main Authors:	E. V. Batorov, P. V. Vasilchenko, E. R. Chernykh
Format:	Artigo
Language:	Russo
Published:	Russian Academy of Sciences, Siberian Branch Publishing House 2025-11-01
Series:	Сибирский научный медицинский журнал
Subjects:	t cell exhaustion anti-pd-1/pd-l1 monoclonal antibodies pd-1 tim-3 lag-3 tigit regulatory t cells
Online Access:	https://sibmed.elpub.ru/jour/article/view/2434
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