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Expanding the genetic code of Mus musculus

Expanding the genetic code with unnatural amino acids in model organisms is a powerful tool for investigatingin vivocellular proteins and processes. Here the authors re-engineer the amber stop codon in laboratory mice to allow site-specific incorporation of unnatural amino acids in target proteins.

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Bibliografische Detailangaben
Hauptverfasser: Songmi Han, Aerin Yang, Soonjang Lee, Han-Woong Lee, Chan Bae Park, Hee-Sung Park
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2017-02-01
Schriftenreihe:Nature Communications
Online-Zugang:https://doi.org/10.1038/ncomms14568
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