Effect of the Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulator Dipraglurant on Motor and Non-Motor Symptoms of Parkinson’s Disease

Parkinson’s disease (PD) patients suffer not only from the primary motor symptoms of the disease but also from a range of non-motor symptoms (NMS) that cause disability and low quality of life. Excessive glutamate activity in the basal ganglia resulting from degeneration of the nigrostriatal dopamin...

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Principais autores:	Mark P. Epping-Jordan, Françoise Girard, Anne-Sophie Bessis, Vincent Mutel, Christelle Boléa, Francis Derouet, Abdelhak Bessif, Brice Mingard, Stéphanie Barbier, Justine S. Paradis, Jean-Philippe Rocher, Robert Lütjens, Mikhail Kalinichev, Sonia Poli
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2023-03-01
סדרה:	Cells
נושאים:	dipraglurant mGlu5 depression anxiety obsessive-compulsive disorder Parkinson’s disease
גישה מקוונת:	https://www.mdpi.com/2073-4409/12/7/1004
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