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Molecular basis of EphA2 recognition by gHgL from gammaherpesviruses

EphA2 is the specific entry receptor for both human γ-herpesviruses Kaposi sarcoma associated herpesvirus (KSHV) and Epstein-Barr virus (EBV). Here, the authors present the crystal structures of the EphA2 ligand binding domain (LBD) bound to the viral glycoprotein gHgL from EBV and KSHV and further...

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Autori principali: Chao Su, Lili Wu, Yan Chai, Jianxun Qi, Shuguang Tan, George F. Gao, Hao Song, Jinghua Yan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2020-11-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-020-19617-9
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