Structure-guided discovery of novel dUTPase inhibitors with anti-Nocardia activity by computational design
The zoonosis caused by Nocardia is increasing seriously. But commonly used antibiotic drugs often lead to resistance. N. seriolae dUTPase (NsdUTPase) plays a key role in the proliferation of Nocardia, and was regarded as a potent drug target. However, there was little report about the NsdUTPase inhi...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis Group
2024-12-01
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| Serie: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Soggetti: | |
| Accesso online: | https://www.tandfonline.com/doi/10.1080/14756366.2024.2411573 |
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