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The role of ADAR1 through and beyond its editing activity in cancer

Abstract Adenosine-to-inosine (A-to-I) editing of RNA, catalyzed by adenosine deaminase acting on RNA (ADAR) enzymes, is a prevalent RNA modification in mammals. It has been shown that A-to-I editing plays a critical role in multiple diseases, such as cardiovascular disease, neurological disorder, a...

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Principais autores: Yue Jiao, Yuqin Xu, Chengbin Liu, Rui Miao, Chunyan Liu, Yilong Wang, Jiao Liu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-01-01
Serier:Cell Communication and Signaling
Fag:
ADAR1
RNA editing
RNA editing-independent
Cancer
Cancer therapy
Online adgang:https://doi.org/10.1186/s12964-023-01465-x
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