RTA-like proteins regulate azole susceptibility by affecting the expression of the oxidoreductase gene oxrA in Aspergillus fumigatus

Abstract Aspergillus fumigatus, a saprophytic fungus and the principal etiologic agent of aspergillosis, is increasingly implicated in drug-resistant infections, posing challenges to clinical management. RTA-like proteins, a distinctive class of transmembrane fungal proteins, are involved in several...

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Auteurs principaux:	Jing Wu, Di Su, Zhongyuan Niu, Sitong Liu, Chenxi Li, Jing Ye, Xiaogang Zhou
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2026-04-01
Collection:	BMC Microbiology
Sujets:	Aspergillus fumigatus RTA-like protein Azole resistance Oxidoreductase Drug efflux pump
Accès en ligne:	https://doi.org/10.1186/s12866-026-04985-x
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