Nanomaterials-mediated lysosomal regulation: a robust protein-clearance approach for the treatment of Alzheimer’s disease

Alzheimer’s disease is a debilitating, progressive neurodegenerative disorder characterized by the progressive accumulation of abnormal proteins, including amyloid plaques and intracellular tau tangles, primarily within the brain. Lysosomes, crucial intracellular organelles responsible for protein d...

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Hlavní autoři:	Mengqi Hao, Jianjian Chu, Tinglin Zhang, Tong Yin, Yuankai Gu, Wendanqi Liang, Wenbo Ji, Jianhua Zhuang, Yan Liu, Jie Gao, You Yin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wolters Kluwer Medknow Publications 2025-02-01
Edice:	Neural Regeneration Research
Témata:	alzheimer’s disease autophagy dysfunction lysosomal acidification lysosomal system nanomaterials neurodegenerative diseases
On-line přístup:	https://journals.lww.com/10.4103/NRR.NRR-D-23-01736
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