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Identification and characterization of a novel glutaminase inhibitor

In humans, there are two forms of glutaminase (GLS), designated GLS1 and GLS2. These enzymes catalyse the conversion of glutamine to glutamate. GLS1 exists as two isozymes: kidney glutaminase (KGA) and glutaminase C (GAC). Several GLS inhibitors have been identified, of which DON (6‐diazo‐5‐oxonorle...

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Autors principals: Henning Cederkvist, Shrikant S. Kolan, Jonas Aakre Wik, Zeynep Sener, Bjørn Steen Skålhegg
Format: Artigo
Idioma:Inglês
Publicat: Wiley 2022-01-01
Col·lecció:FEBS Open Bio
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Accés en línia:https://doi.org/10.1002/2211-5463.13319
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