Intravenously administered interleukin-7 to reverse lymphopenia in patients with septic shock: a double-blind, randomized, placebo-controlled trial

Abstract Background Profound lymphopenia is an independent predictor of adverse clinical outcomes in sepsis. Interleukin-7 (IL-7) is essential for lymphocyte proliferation and survival. A previous phase II study showed that CYT107, a glycosylated recombinant human IL-7, administered intramuscularly...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Thomas Daix, Armelle Mathonnet, Scott Brakenridge, Pierre-François Dequin, Jean-Paul Mira, Frederique Berbille, Michel Morre, Robin Jeannet, Teresa Blood, Jacqueline Unsinger, Jane Blood, Andrew Walton, Lyle L. Moldawer, Richard Hotchkiss, Bruno François
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2023-03-01
coleção:	Annals of Intensive Care
Assuntos:	Sepsis Immune restoration Lymphocyte Interleukin-7
Acesso em linha:	https://doi.org/10.1186/s13613-023-01109-w
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!