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Importance of the collagen adhesin ace in pathogenesis and protection against Enterococcus faecalis experimental endocarditis.

Ace is an adhesin to collagen from Enterococcus faecalis expressed conditionally after growth in serum or in the presence of collagen. Here, we generated an ace deletion mutant and showed that it was significantly attenuated versus wild-type OG1RF in a mixed infection rat endocarditis model (P<0.000...

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Detalhes bibliográficos
Principais autores: Kavindra V Singh, Sreedhar R Nallapareddy, Jouko Sillanpää, Barbara E Murray
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2010-01-01
Colecção:PLoS Pathogens
Acesso em linha:http://europepmc.org/articles/PMC2798748?pdf=render
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