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CRISPR-Cas13a-powered electrochemical biosensor for the detection of the L452R mutation in clinical samples of SARS-CoV-2 variants

Abstract Since the end of 2019, a highly contagious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has deprived numerous lives worldwide, called COVID-19. Up to date, omicron is the latest variant of concern, and BA.5 is replacing the BA.2 variant to become the main s...

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Principais autores: Zhi Chen, Chenshuo Wu, Yuxuan Yuan, Zhongjian Xie, Tianzhong Li, Hao Huang, Shuang Li, Jiefeng Deng, Huiling Lin, Zhe Shi, Chaozhou Li, Yabin Hao, Yuxuan Tang, Yuehua You, Omar A. Al-Hartomy, Swelm Wageh, Abdullah G. Al-Sehemi, Ruitao Lu, Ling Zhang, Xuechun Lin, Yaqing He, Guojun Zhao, Defa Li, Han Zhang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-04-01
Serier:Journal of Nanobiotechnology
Fag:
CRISPR
SARS-CoV-2 BA.5 variant
Electrochemical biosensor
MXene
Online adgang:https://doi.org/10.1186/s12951-023-01903-5
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