Synthesis of the 3’-O-sulfated TF antigen with a TEG-N3 linker for glycodendrimersomes preparation to study lectin binding

The synthesis of gram quantities of the TF antigen (β-ᴅ-Gal-(1→3)-α-ᴅ-GalNAc) and its 3’-sulfated analogue with a TEG-N3 spacer attached is described. The synthesis of the TF antigen comprises seven steps, from a known N-Troc-protected galactosamine donor, with an overall yield of 31%. Both the spac...

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Hlavní autoři:	Mark Reihill, Hanyue Ma, Dennis Bengtsson, Stefan Oscarson
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Beilstein-Institut 2024-01-01
Edice:	Beilstein Journal of Organic Chemistry
Témata:	regioselective sulfation thioglycoside donors thomsen–friedenreich antigen
On-line přístup:	https://doi.org/10.3762/bjoc.20.17
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