Cerebral blood flow in presymptomatic MAPT and GRN mutation carriers: A longitudinal arterial spin labeling study

Objective: Frontotemporal dementia (FTD) is characterized by behavioral disturbances and language problems. Familial forms can be caused by genetic defects in microtubule-associated protein tau (MAPT), progranulin (GRN), and C9orf72. In light of upcoming clinical trials with potential disease-modify...

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Principais autores:	Elise G.P. Dopper, PhD, Vicky Chalos, Eidrees Ghariq, Tom den Heijer, MD PhD, Anne Hafkemeijer, MSc, Lize C. Jiskoot, MSc, Inge de Koning, PhD, Harro Seelaar, MD PhD, Rick van Minkelen, PhD, Matthias J.P. van Osch, PhD, Serge A.R.B. Rombouts, PhD, John C. van Swieten, MD PhD
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2016-01-01
Colecção:	NeuroImage: Clinical
Assuntos:	Frontotemporal dementia Arterial spin labeling Cerebral blood flow Presymptomatic
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2213158216301371
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