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Dominant sequences of human major histocompatibility complex conserved extended haplotypes from HLA-DQA2 to DAXX.

We resequenced and phased 27 kb of DNA within 580 kb of the MHC class II region in 158 population chromosomes, most of which were conserved extended haplotypes (CEHs) of European descent or contained their centromeric fragments. We determined the single nucleotide polymorphism and deletion-insertion...

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Principais autores: Charles E Larsen, Dennis R Alford, Michael R Trautwein, Yanoh K Jalloh, Jennifer L Tarnacki, Sushruta K Kunnenkeri, Dolores A Fici, Edmond J Yunis, Zuheir L Awdeh, Chester A Alper
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2014-10-01
Serier:PLoS Genetics
Online adgang:http://europepmc.org/articles/PMC4191933?pdf=render
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