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From the Ganglioside GQ1b? to Glycomimetic Antagonists of the Myelin-Associated Glycoprotein (MAG)

The tetrasaccharide 4, a substructure of ganglioside GQ1b?, shows a remarkable affinity for the myelin-associated glycoprotein (MAG) and was therefore selected as starting point for a lead optimization program. In our search for structurally simplified and pharmacokinetically improved mimi...

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Autors principals: Beat Ernst, Oliver Schwardt, Stefanie Mesch, Matthias Wittwer, Gianluca Rossato, Angelo Vedani
Format: Artigo
Idioma:Alemão
Publicat: Swiss Chemical Society 2010-02-01
Col·lecció:CHIMIA
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Accés en línia:https://www.chimia.ch/chimia/article/view/4791
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