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An Overview of CD133 as a Functional Unit of Prognosis and Treatment Resistance in Glioblastoma

Biomarkers for resistance in Glioblastoma multiforme (GBM) are lacking, and progress in the clinic has been slow to arrive. CD133 (prominin-1) is a membrane-bound glycoprotein on the surface of cancer stem cells (CSCs) that has been associated with poor prognosis, therapy resistance, and tumor recur...

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Principais autores: Thomas Joyce, Sarisha Jagasia, Erdal Tasci, Kevin Camphausen, Andra Valentina Krauze
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2023-09-01
Series:Current Oncology
Assuntos:
CD133
stem cell marker
glioblastoma
chemo/radioresistance
recurrence
omics
Acceso en liña:https://www.mdpi.com/1718-7729/30/9/601
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