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Evaluation of serum neurofilament light chain, GFAP, and peripherin as biomarkers in hereditary transthyretin amyloidosis

Abstract Early diagnosis and accurate monitoring of disease progression are crucial for timely therapeutic intervention in hereditary transthyretin amyloidosis (ATTRv). Neurofilament light chain (NfL) has emerged as a sensitive biomarker of neuroaxonal injury across neurodegenerative disorders. This...

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Autori principali: Intissar Anan, Gabriella Johannson, Björn Pilebro, Jonas Wixner, Victoria Heldestad, Sandra Arvidsson, Malin Olsson
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2026-06-01
Serie:Scientific Reports
Soggetti:
Transthyretin
Amyloidosis
Neurofilament light chain
Neuropathy
Biomarker
Accesso online:https://doi.org/10.1038/s41598-026-56777-y
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