Herbal NF-κB Inhibitors Sensitize Rituximab-Resistant B Lymphoma Cells to Complement-Mediated Cytolysis

BackgroundDrug resistance remains a serious challenge to rituximab therapy in B-NHL (B cell non-Hodgkin’s lymphoma). CDC (complement-dependent cytotoxicity) has been proposed as a major antitumor mechanism of rituximab, and direct abrogation of CD59 function partially restores rituximab sensitivity...

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Detalhes bibliográficos

Principais autores:	Xiaowen Ge, Yiqun Du, Jianfeng Chen, Na Zhu, Jiamei Yao, Xin Zhang, Na Wang, Yujing Sun, Feng Gao, Weiguo Hu, Yingyong Hou
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-12-01
coleção:	Frontiers in Oncology
Assuntos:	rituximab resistance CD59 NF-κB curcumin perillyl alcohol
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fonc.2021.751904/full
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