Potency and Selectivity of SMAC/DIABLO Mimetics in Solid Tumor Therapy

Aiming to promote cancer cell apoptosis is a mainstream strategy of cancer therapy. The second mitochondria-derived activator of caspase (SMAC)/direct inhibitor of apoptosis protein (IAP)-binding protein with low pI (DIABLO) protein is an essential and endogenous antagonist of inhibitor of apoptosis...

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Principais autores:	Xiao-Yun Zhao, Xiu-Yun Wang, Qi-Yao Wei, Yan-Ming Xu, Andy T. Y. Lau
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2020-04-01
Series:	Cells
Assuntos:	inhibitor of apoptosis protein (IAP) second mitochondria-derived activator of caspase (SMAC) direct IAP-binding protein with low pI (DIABLO) SMAC mimetics (SMs) clinical trial therapy
Acceso en liña:	https://www.mdpi.com/2073-4409/9/4/1012
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