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Anti-proliferative effect of cytohesin inhibition in gefitinib-resistant lung cancer cells.

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI), such as gefitinib, have been proven to efficiently inhibit the proliferation of a subset of non small-cell lung cancers (NSCLC). Unfortunately, the majority of NSCLC expressing wild type EGFR is primarily resistant to EGFR-TKI...

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Autors principals: Anke Bill, Anton Schmitz, Katharina König, Lukas C Heukamp, Jeffrey S Hannam, Michael Famulok
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2012-01-01
Col·lecció:PLoS ONE
Accés en línia:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22815959/?tool=EBI
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