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Wnt/β-Catenin Signaling Promotes Differentiation of Ischemia-Activated Adult Neural Stem/Progenitor Cells to Neuronal Precursors

Modulating endogenous regenerative processes may represent a suitable treatment for central nervous system (CNS) injuries, such as stroke or trauma. Neural stem/progenitor cells (NS/PCs), which naturally reside in the subventricular zone (SVZ) of the adult brain, proliferate and differentiate to oth...

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Uloženo v:
Hlavní autoři: Jan Kriska, Lucie Janeckova, Denisa Kirdajova, Pavel Honsa, Tomas Knotek, David Dzamba, Denisa Kolenicova, Olena Butenko, Martina Vojtechova, Martin Capek, Zbynek Kozmik, Makoto Mark Taketo, Vladimir Korinek, Miroslava Anderova
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021-02-01
Edice:Frontiers in Neuroscience
Témata:
Wnt signaling
transgenic mouse
neural stem/progenitor cell
focal cerebral ischemia
adult neurogenesis
gliogenesis
On-line přístup:https://www.frontiersin.org/articles/10.3389/fnins.2021.628983/full
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