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Phosphorylation of a Myosin Motor by TgCDPK3 Facilitates Rapid Initiation of Motility during Toxoplasma gondii egress.

Members of the family of calcium dependent protein kinases (CDPK's) are abundant in certain pathogenic parasites and absent in mammalian cells making them strong drug target candidates. In the obligate intracellular parasite Toxoplasma gondii TgCDPK3 is important for calcium dependent egress from th...

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Principais autores: Rajshekhar Y Gaji, Derrick E Johnson, Moritz Treeck, Mu Wang, Andy Hudmon, Gustavo Arrizabalaga
格式: Artigo
語言:Inglês
出版: Public Library of Science (PLoS) 2015-01-01
叢編:PLoS Pathogens
在線閱讀:https://doi.org/10.1371/journal.ppat.1005268
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