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Biased IL-2 signals induce Foxp3-rich pulmonary lymphoid structures and facilitate long-term lung allograft acceptance in mice

IL-2/anti-IL-2 antibody complexes have been shown to facilitate the process of graft acceptance in transplantation. Here the authors use a mouse allograft model to show that IL-2 complexes promote graft acceptance and formation of inducible lymphoid structures containing Treg cells in transplanted l...

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Bibliografski detalji
Glavni autori: Yoshito Yamada, Tuan Thanh Nguyen, Daniela Impellizzieri, Katsutaka Mineura, Rintaro Shibuya, Alvaro Gomariz, Martina Haberecker, Jakob Nilsson, César Nombela-Arrieta, Wolfgang Jungraithmayr, Onur Boyman
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2023-03-01
Serija:Nature Communications
Online pristup:https://doi.org/10.1038/s41467-023-36924-z
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